Use of CBD in Veterinary medicine:

Research:

There has been an increase in the number of research projects and scientific publications on cannabidiol and other cannabinoids in pets since the end of 2010. As of December 2020, there are no hemp-derived, cannabinoid-rich registered veterinary products in any of the major regions. In the United States and other regions, however, many veterinary nutraceutical products are available OTC. The lack of clarity in regulations governing the dosage of veterinary cannabis food leads to a flood of products of questionable quality on the market, which can pose a risk to the well-being of pets and owners. One can easily get the best cbd capsules at offline and online stores. The use of CBD products is used for any purposes like cbd gummies for anxiety, cbd oil for anxiety and many others.

To better understand the benefits of CBD and related compounds for the quality of life of animals, companies specializing in CBD products for animals are funding research projects.

Epilepsy:

From the results observed in scientific studies and reviews in humans with drugs such as Epidiolex and Sativex, it can be expected that CBD-based products will be helpful in managing seizures in dogs. However, despite several case reports submitted by veterinary neurologists supporting the benefits of CBD as adjuvant therapy, controlled studies published as of December 2020 did not show a statistically significant reduction in the number of seizures in groups receiving CBD. Further research is needed in this area before any clear conclusions can be reached.

Pharmacokinetic:

The oral bioavailability of CBD varies greatly between species and is linked to the time of presentation and administration. A 24-hour kinetic examination in dogs showed that there is an absorption of cannabidiol acid (CBDA), and this molecule is at least twice as absorbed as CBD after oral ingestion. It was found that the major metabolites of CBD in humans are not prevalent in dogs, whereas 6-OH-CBD was found to be the primary metabolite in dogs receiving CBD-enriched cannabis-derived herbal extracts, suggesting canine and human CBD metabolism.

Safety:

An increase in alkaline phosphatase (ALP) has been reported in various canine studies. A 39-week study evaluating doses of 0, 10, 50, and 100 mg/kg of CBD in dogs found an 8-fold increase in ALP in the 100 mg/kg group and a 1.5-fold increase in alanine aminotransferase. (ALT) in the 50 mg/kg and 100 mg/kg groups.